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Tadalafil is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection). It is in a class of drugs called phosphodiesterase inhibitors that also includes sildenafil (Viagra) and vardenafil (Levitra).
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Product details
Cialis (Tadalafil)
Cialis is a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men.
Take Cialis exactly as your doctor prescribes. Cialis comes in different doses (5 mg, 10 mg, and 20 mg). For most men, the recommended starting Cialis dose is 10 mg. Cialis should be taken no more than once a day. Your doctor will prescribe the dose that is right for you.
Tadalafil is an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection). It is in a class of drugs called phosphodiesterase inhibitors that also includes sildenafil (Viagra) and vardenafil (Levitra).
Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, and, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis.
Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase, to produce cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the penis, respectively, and causing the erection. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the penis, and the erection ends. Tadalafil prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of cGMP leads to a more prolonged engorgement of the penis with blood.
Tadalafil was approved by the FDA in November, 2003.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Store Cialis at room temperature between 59 and 86 F (15 and 30 C).
Cialis can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines such as nitrates and alpha-blockers, and recreational drugs that contain nitrates called "poppers". A sudden drop in your blood pressure could cause you to become dizzy, faint, or have a heart attack or stroke. Until you are certain how you are affected by Cialis, use caution when driving or operating heavy machinery. Cialis contains some lactose and should not be taken by patients who are lactose intolerant. Also, during treatment you should avoid grapefruit juice. Taking Cialis with grapefruit juice can increase your chances of experiencing undesirable side effects. If you are taking medications with nitrates or nitric oxide, have uncontrolled blood pressure (high or low), or if you have a history of stroke or heart attack DO NOT take Cialis.
The most common side effects with Cialis are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Patients who get back pain and muscle aches usually get it 12 to 24 hours after taking Cialis. Back pain and muscle aches usually go away by themselves within 48 hours. Call your doctor if you get a side effect that bothers you or one that will not go away.
If you experience any of the following serious side effects, stop taking tadalafil and seek emergency medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
chest pain or irregular heartbeats;
dizziness, nausea, or angina (pain, tightness, discomfort, numbness, or tingling in the chest, arms, neck, or jaw);
swelling of the ankles or legs;
shortness of breath;
prolonged or severe dizziness; or
a prolonged (lasting longer than 4 hours) or painful erection.
Other, less serious side effects may be more likely to occur. Continue to take tadalafil and talk to your doctor if you experience
headache;
indigestion;
back pain;
muscle aches;
flushing;
stuffy or runny nose; or
temporary blue tint in vision or difficulty telling the difference between the colors blue and green (uncommon).
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.